The generation of
carbon-nitrogen bonds is a significant process in organic chemistry. Nearly
80% of all pharmaceuticals contain carbon-nitrogen bonds, therefore creating
new methods in carbon-nitrogen bond formation can have a significant impact
on many industries.
In
this project we develop new titanium and zirconium catalysts that facilitate
the reaction of a primary amine (NH2R) and alkyne (carbon-carbon
triple bond) to produce new carbon-nitrogen bonds.
KU Chemistry Undergraduate
Research with
Dr. Doug Swartz
Hydroamination
Students
that work on this project do research at the interface of organic and inorganic
chemistry. They learn many organic synthesis techniques as well as the skill
of handling air and moisture sensitive molecules.
