CHM 312                         Biochemistry II               Spring 2008

 

Instructor:        Dr. Matthew Junker    

314 Boehm Science Center

Phone:  610-683-4199      Email:  junker@kutztown.edu

Office hours:  Tue. 3-4pm; Wed. 2-5pm; Fri. 11am-12pm

Lecture time and location:  M, W, F 1:00 – 1:50, Boehm 261

 

Textbook:        Lehninger Principles of Biochemistry, 4th edition, by David L. Nelson and

Michael M. Cox, W. H. Freeman and Co., ISBN: 0-7167-4339-6.

Textbook website:  www.whfreeman.com/lehninger

Lecture notes posted online under Blackboard:  http://blackboard.kutztown.edu/

Pre-requisites:  Biochemistry I (CHM 310)

Co-requisite:  CHM 313 (Biochemistry Laboratory II)

 

Grading:          The average of 4 exams (each worth 100 points) will be 80% of final score

                        Each problem set will be 1% of final score

                        The total lab score (CHM 313) and the problem sets will be 20% of final score

            Final scores will be scaled to 100 points

            Minimum guaranteed curve (final curve can be more generous, but not less):

                                    score           grade

                                    90-100             A

                                    80-90               B

                                    70-80               C

                                    60-70               D

                                    <60                  F

 

Course objectives:  Upon successful completion of this course, a student will be able to

     - Explain the metabolic pathways for the synthesis and breakdown of the major types of

       biomolecules (carbohydrates, amino acids, nucleotides, and lipids)

     - Explain the integration and regulation of the major metabolic pathways

     - Predict how changes in specific cellular conditions would alter the major metabolic

       pathways

     - Predict how changes in specific metabolic reactions would alter overall cellular

       metabolism

 

ADA Notice:  Any student who has a need for accommodation based on the impact of a disability should contact me privately to discuss the specific situation as soon as possible.  Students should also contact KU Disability Resources and Services at 610-683-4108 or in Stratton 215 to coordinate accommodations. 

 

Lecture schedule:

 

Date

 

Topic

Lehninger

Chapter

Jan. 14

Principles of bioenergetics

13 & pp. 481-488

Jan. 16

Principles of bioenergetics

13

Jan. 18

Principles of bioenergetics

13

Jan. 23

Principles of bioenergetics

13

Jan. 25

Principles of bioenergetics

13

Jan. 28

Glycolysis

14

Jan. 30

Glycolysis

14

Feb. 1

Glycolysis

14

Feb. 4

Gluconeogenesis

14

Feb. 6

Gluconeogenesis

14

Feb. 8

Pentose phosphate pathway

14

Feb. 11

EXAM 1 (material thru. Feb. 8)

 

Feb. 13

Metabolic regulation: glucose and glycogen

15

Feb. 15

Metabolic regulation: glucose and glycogen

15

Feb. 19 (Tue!)

Citric acid cycle

16

Feb. 20

Citric acid cycle

16

Feb. 22

Citric acid cycle

16

Feb. 25

Fatty acid catabolism

17

Feb. 27

Fatty acid catabolism

17

Feb. 29

Fatty acid catabolism

17

Mar. 3

Amino acid catabolism

18

Mar. 5

Amino acid catabolism

18

Mar. 7

EXAM 2 (material Feb. 13 - Mar. 5)

 

Mar. 10-14

NO CLASS: Spring Break

 

Mar. 17

Oxidative phosphorylation

19

Mar. 19

Oxidative phosphorylation

19

Mar. 21

Oxidative phosphorylation

19

Mar. 24

NO CLASS: Reading Day

 

Mar. 26

Oxidative phosphorylation

19

Mar. 28

Oxidative phosphorylation

19

Mar. 31

Oxidative phosphorylation

19

Apr. 2

Photophosphorylation

19

Apr. 4

Photophosphorylation

19

Apr. 7

Photophosphorylation

19

Apr. 9

Carbohydrate biosynthesis

20

Apr. 11

EXAM 3 (material Mar. 17 - Apr. 9)

 

Apr. 14

Carbohydrate biosynthesis

20

Apr. 16

Lipid biosynthesis

21

Apr. 18

NO CLASS: Spring Recess

 

Apr. 21

Lipid biosynthesis

21

Apr. 23

Lipid biosynthesis

21

Apr. 25

Nitrogen metabolism

22

Apr. 28

Nitrogen metabolism

22

Apr. 30

Amino acid biosynthesis

22

May 2

Nucleotide biosynthesis

22

May 7 (Wed.)

FINAL EXAM (material Apr. 14- May 2)   NOTE: 8:00 am