CHM 310                         Biochemistry I                        Fall 2008

 

Instructor:        Dr. Matthew Junker    

314 Boehm Science Center

Phone:  610-683-4199      Email:  junker@kutztown.edu

Office hours:  Tues., 2-3pm;  Wed. 2-5pm;  Fri. 10-11am

Lecture time and location:  M, W, F 1:00 – 1:50, Boehm 261

 

Textbook:        Lehninger Principles of Biochemistry, 5th edition, by David L. Nelson and

Michael M. Cox, W. H. Freeman and Co., ISBN:  0-7167-7108-X.

Textbook website:   www.whfreeman.com/lehninger

Lecture notes posted online under Blackboard:  http://blackboard.kutztown.edu/

Pre-requisites:  Organic Chemistry I & II (CHM 214 & 216)

Co-requisite:  CHM 311 (Biochemistry Laboratory I)

 

Grading:          The average of 4 exams (each worth 100 points) will be 80% of final score

                        The average of all problem sets will be 5% of final score 

                        The total lab score (CHM 311) will be 15% of final score

            Final scores will be scaled to 100 points

            Minimum guaranteed curve (final curve can be more generous, but not less):

                                    score           grade

                                    90-100             A

                                    80-90               B

                                    70-80               C

                                    60-70               D

                                    <60                  F

 

Course objectives:  Upon successful completion of this course, a student will be able to

     - Describe the distinguishing structural and chemical properties of the major types of

             biomolecules (amino acids, proteins, carbohydrates, lipids, and nucleic acids)

     - Relate the chemical properties of each type of biomolecule to its physiological function

     - Explain the primary, secondary, tertiary, and quaternary structures of the molecular

       components of cells

     - Describe protein and lipid dynamics and perform pertinent calculations

 

ADA Notice:  Any student who needs accommodation for a disability should contact me for assistance early in the semester.  Students should also contact KU Disability Resources and Services at 610-683-4108 or in Stratton 215. 

 

Lecture schedule:

 

Date

 

Topic

Lehninger

Chapter

Aug. 27

Overview, major types of biomolecules

1

Aug. 29

Thermodynamics in biochemistry

1

Sept. 2 (Tues!)

Water and molecular forces in aqueous environments

2

Sept. 3

Water: pH, and acid-base chemistry I

2

Sept. 5

Water: pH, and acid-base chemistry II

2

Sept. 8

Amino acids I

3

Sept. 10

Amino acids II

3

Sept. 12

Protein structure I

4

Sept. 15

Protein structure II

4

Sept. 17

Protein methods (Chapt. 3, part 2)

3

Sept. 19

Protein methods (Chapt. 3, part 2)

3

Sept. 22

EXAM 1

 

Sept. 24

Protein structure III

4

Sept. 26

Protein structure IV

4

Sept. 29

Protein structure V

4

Oct. 1

Protein function I

5

Oct. 3

Protein function II

5

Oct. 6

Protein function III

5

Oct. 8

Protein function IV

5

Oct. 10

Enzymes I

6

Oct. 13

COLUMBUS DAY- NO CLASS

 

Oct. 15

Enzymes II

6

Oct. 17

EXAM 2

 

Oct. 20

Enzymes III

6

Oct. 22

Enzymes IV

6

Oct. 24

Enzymes V

6

Oct. 27

Enzymes VI

6

Oct. 29

Carbohydrates I

7

Oct. 31

Carbohydrates II

7

Nov. 3

Carbohydrates III

7

Nov. 5

Nucleic acids I

8

Nov. 7

Nucleic acids II

8

Nov. 10

EXAM 3

 

Nov. 12

Nucleic acids III

8

Nov. 14

DNA technologies

9

Nov. 17

Lipids I

10

Nov. 19

Lipids II

10

Nov. 21

Lipids III

10

Nov. 24

Membranes and transport I

11

Nov. 26

THANKSGIVING – NO CLASS

 

Nov. 28

THANKSGIVING – NO CLASS

 

Dec. 1

Membranes and transport II

11

Dec. 3

Membranes and transport III

11

Dec. 5

Membranes and transport IV

11

Dec. 10 (Wed.)

FINAL EXAM     8:00 am - 10:00 am